Featured Publications

Hwang MS, Miller MS, Thirawatananond P, Douglass J, Wright KM, Hsiue EH, Mog BJ, Aytenfisu TY, Murphy MB, Aitana Azurmendi P, Skora AD, Pearlman AH, Paul S, DiNapoli SR, Konig MF, Bettegowda C, Pardoll DM, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S, Gabelli SB. Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens. Nat Commun. 2021 Sep 6;12(1):5271. doi: 10.1038/s41467-021-25605-4. PMID: 3448947

Han-Chung Hsie E, Wright KM, Douglas J, Hwang MS, Mog BJ, Pearlman AH, Paul S, DiNapoli SR, Konig MF, Wang Q, Schaefer A, Miller MS, Skora AD, Azurmendi PA, Murphy MB, Liu Q, Watson E, Li Y, Pardoll DM, Bettegowda C, Papadopoulos N, Kinzler KW, Vogelstein B, Gabelli SB*, Zhou S. Targeting a neoantigen derived from a common TP53 mutation. Science  01 Mar 2021:eabc8697DOI: 10.1126/science.abc8697

Paul S, Pearlman AH, Douglass J, Mog BJ, Han-Chung Hsie E, Hwang MS, DiNapoli SR, Konig MF, Brown PP, Wright KM, Sur S, Gabelli SB, Li Y, Ghiaur G, Pardoll DM, Papadopoulos, Bettegowda C, Kinzler KW, Zhou S, Vogelstein B. TCR beta chain-directed bispecific antibodies for the treatment of T cell cancers. Sci Transl Med. 2021 Mar 1. Epub.

Douglass J, Han-Chung Hsiue E, Mog BJ, Hwang MS, DiNapoli SR, Pearlman AH, Miller MS, Wright KM, Azurmendi PA, Wang Q, Paul S, Schaefer A, Skora AD, Dal Molin M, Konig MF, Liu Q, Watson E, Li Y, Murphy MB, Pardoll DM, Bettegowda C, Papadopoulos N, Gabelli SB, Kinzler KW, Vogelstein B, Zhou Bispecific antibodies targeting mutant RAS neoantigens. Science Immunology 01 Mar 2021

Nathan S, Gabelli SB*, Yoder JB, Srinivasan S, Aldrich RW, Tomaselli GF, Ben-Johny M, Amzel LM. Structural Basis of cytoplasmic Nav1.5 and Nav1.4 regulation. J Gen Physiol (2021) 153 (1): e202012722. https://doi.org/10.1085/jgp.202012722

Chakrabarti M, Gabelli  SB,  Amzel  LM. Allosteric Activation of PI3Kα Results in Dynamic Access to Catalytically Competent Conformations. Structure. 2020. PMID: 32049032

Maheshwari S, Kim YS, Aripirala S, Murphy M, Amzel LM, Gabelli SB*. Identifying Structural Determinants of Product Specificity in Leishmania major Farnesyl Diphosphate Synthase. 2020 Jul 28;59(29):2751-2759. doi: 10.1021/acs.biochem.0c00432. Epub 2020 Jul 1

Miller MS, Maheshwari S, Shi W, Gao Y, Chu N, Soares AS, Cole PA, Amzel LM, Fuchs MR, Jakoncic J, Gabelli SB. Getting the Most Out of Your Crystals: Data Collection at the New High-Flux, Microfocus MX Beamlines at NSLS-II. Molecules. 2019 Jan 30;24(3). pii: E496. doi: 10.3390/molecules24030496.

Featured News

August 28, 2021

We have lost a true giant of the basic sciences, fervent supporter of public education. Mario Amzel, was a renaissance... Read More